av P Umate · 2011 · Citerat av 90 — Helicases are motor proteins which catalyze the unwinding of duplex nucleic acids a mutant DHX16 with mutation in the helicase domain accumulated unspliced, A BLAST against human RefSeq protein database on NCBI with individual

av J Johansson · 2021 · Citerat av 1 — One method uses biomimetics in which the spider silk proteins (spidroins) (18−21) The terminal domains are unique to spidroins and regulate silk of a section of a repetitive region using the Zipper Database (ref (54)) for a

Our database, Pfam, consists of parts A and B. Pfam‐A is curated and contains well‐characterized protein domain families with high quality alignments, which are maintained by using manually checked seed alignments and HMMs to find and align all members. Jun 28, 2018 Introduction. A protein domain is a conserved and functional unit of a protein that can fold independently and has distinct functions. Most proteins Dec 18, 2019 A protein domain is typically associated with a function, such as enzyme catalysis or nucleic‐acid binding, and is a unit of molecular evolution; via Feb 22, 2018 A domain is a segment of protein that has reserved structural or functional properties.

Sequence clusters. Proteomes. Protein sets from fully sequenced genomes. Annotation systems. Systems used to automatically annotate proteins with high accuracy: UniRule (Expertly curated rules) ProDom is a database of protein domain families based on the automatic clustering of sequences by similarity . Because it has not been updated since December 2015, we removed ProDom from InterPro in release 74.0.

DOMINE is a database of protein domain (domain-domain) interactions inferred from PDB entries, and those that are predicted by 8 different computational approaches using Pfam domain definitions. 2. What is a domain? Domain is a structural or functional subunit of a protein.

homology assisted identification of inhibitor of RNA binding against 2019-nCoV N-protein (N terminal domain) CDKD: a clinical database of kidney diseases. av M Jönsson · 2002 · Citerat av 242 — By contrast, loss of Wnt-5a protein in 24% of the invasive lobular found by searching the patient database comprising females who had had of a collagen-binding receptor referred to as the discoidin domain receptor 1 (8) .

av M Jönsson · 2002 · Citerat av 242 — By contrast, loss of Wnt-5a protein in 24% of the invasive lobular found by searching the patient database comprising females who had had of a collagen-binding receptor referred to as the discoidin domain receptor 1 (8) .

Crystal structure of human DECH-box RNA Helicase MDA5 (Melanoma differentiation-associated protein 5), DECH-domain · Classification: HYDROLASE 11 mars 2008 — Structure of Protein Tyrosine Kinase 2 Beta (PTK2B) Kinase domain. To be published. Macromolecules. Find similar proteins We used the Automatic Domain Decomposition Algorithm (ADDA) to generate a database of protein domain families with complete coverage of all protein 27 okt. 2016 — Genes 86" database (or later if they have updated the database after this writing). How many unique protein-coding genes are there then?

DOMINE is a database of known and predicted protein domain (domain-domain) interactions. It contains interactions inferred from PDB entries, and those that are predicted by 13 different computational approaches using Pfam domain definitions. Database of protein domains, families and functional sites.
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How many unique protein-coding genes are there then? There is support for limiting to genes containing a "transmembrane domain".

Enter protein or nucleotide query as accession, gi, or sequence in FASTA format. For … Pfam protein domain database.

An evidence describes the source of an annotation, e.g.
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The InterPro database (https://www.ebi.ac.uk/interpro/) provides an integrative classification of protein sequences into families, and identifies functionally important domains and conserved sites. InterProScan is the underlying software that allows protein and nucleic acid sequences to be searched against InterPro's signatures.

av M Jönsson · 2002 · Citerat av 242 — By contrast, loss of Wnt-5a protein in 24% of the invasive lobular found by searching the patient database comprising females who had had of a collagen-binding receptor referred to as the discoidin domain receptor 1 (8) .

Conserved Domain Database (CDD) CDD is a protein annotation resource that consists of a collection of well-annotated multiple sequence alignment models for ancient domains and full-length proteins. These are available as position-specific score matrices for fast identification of conserved domains in protein sequences via RPS-BLAST. Search for Conserved Domains within a protein or coding nucleotide sequence. Enter protein or nucleotide query as accession, gi, or sequence in FASTA format. For … Pfam protein domain database.

An evidence describes the source of an annotation, e.g. an experiment that has been published in the scientific literature, an orthologous protein, a record from another database, etc.

Sequence clusters.

DOMINE is a database of protein domain (domain-domain) interactions inferred from PDB entries, and those that are predicted by 8 different computational approaches using Pfam domain definitions. 2. What is a domain? Domain is a structural or functional subunit of a protein.

av M Jönsson · 2002 · Citerat av 242 — By contrast, loss of Wnt-5a protein in 24% of the invasive lobular found by searching the patient database comprising females who had had of a collagen-​binding receptor referred to as the discoidin domain receptor 1 (8) .

av M Jönsson · 2002 · Citerat av 242 — By contrast, loss of Wnt-5a protein in 24% of the invasive lobular found by searching the patient database comprising females who had had of a collagen-​binding receptor referred to as the discoidin domain receptor 1 (8) .

av M Jönsson · 2002 · Citerat av 242 — By contrast, loss of Wnt-5a protein in 24% of the invasive lobular found by searching the patient database comprising females who had had of a collagen-binding receptor referred to as the discoidin domain receptor 1 (8) .

av M Jönsson · 2002 · Citerat av 242 — By contrast, loss of Wnt-5a protein in 24% of the invasive lobular found by searching the patient database comprising females who had had of a collagen-binding receptor referred to as the discoidin domain receptor 1 (8) .